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KMID : 0613820080180070999
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Journal of Life Science
2008 Volume.18 No. 7 p.999 ~ p.1004
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Effect of Bulnesia sarmienti Water Extracts on Lipid Metabolism in Neonatally Streptozotocin- Induced Diabetic Rats
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Park Chang-Ho
Lee Gee-Dong
Kim Jung-Ok
Kim Kil-Soo
Lee Won-Young
Hong Joo-Heon
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Abstract
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The effects of Bulnesia sarmienti water extract on lipid metabolism were investigated in type-2 diabetes rats. The rats were fed a basal diet and B. sarmienti water extract for 8 weeks. The rats were randomly assigned to each treatment group : normal, control, two kinds of treatment group (BW1: 0.9 ㎎/ml, BW2: 1.8 ㎎/ml). After 8 weeks of experimental diets consumption, the body weights and food efficiency ratio of B. sarmienti water extract fed groups were not different from those in the control group. The concentrations of total-cholesterol, LDL-cholesterol, and triglyceride in blood plasma were significantly decreased in the B. sarmienti water extract groups comparison to the control group. Although blood glucose control effects were not observed, the B. sarmienti water extract feeds were highly effective in lowering the levels of blood lipid substances such as triglycerides, total-cholesterol, and LDL-cholesterol.
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KEYWORD
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Bulnesiasarmienti, total-cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride
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